Reactivating Memories for Consolidation
نویسندگان
چکیده
The consolidation of memory is thought to occur via a hippocampal-neocortical dialog involving reactivation of memory patterns in the hippocampus during sharp-wave ripples. In this issue of Neuron, Nakashiba et al. demonstrate that CA3 output is required for consolidation of contextual fear memory. They also show that lack of CA3 output results in a decrease in ripple-related reactivation, providing additional evidence for a role of ripple-related reactivation in the consolidation process.
منابع مشابه
A Dream Model: Reactivation and Re-encoding Mechanisms for Sleep-dependent Memory Consolidation
We humans spend almost a third of our lives asleep, and there is mounting evidence that sleep not only maintains, but actually improves many of our cognitive functions. Memory consolidation–the process of crystallizing and integrating memories into knowledge and skills–is particularly benefitted by sleep. We survey the evidence that sleep aids memory consolidation in various declarative and imp...
متن کاملStrengthening individual memories by reactivating them during sleep.
While asleep, people heard sounds that had earlier been associated with objects at specific spatial locations. Upon waking, they recalled these locations more accurately than other locations for which no reminder cues were provided. Consolidation thus operates during sleep with high specificity and is subject to systematic influences through simple auditory stimulation.
متن کاملBoosting Vocabulary Learning by Verbal Cueing During Sleep.
Reactivating memories during sleep by re-exposure to associated memory cues (e.g., odors or sounds) improves memory consolidation. Here, we tested for the first time whether verbal cueing during sleep can improve vocabulary learning. We cued prior learned Dutch words either during non-rapid eye movement sleep (NonREM) or during active or passive waking. Re-exposure to Dutch words during sleep i...
متن کاملRunning head: REACTIVATING NOVEL WORDS DURING SLEEP 1 Manuscript in press in Neurobiology of Learning and Memory Targeted memory reactivation of newly learned words during sleep triggers REM-mediated integration of new memories and existing knowledge
Recent memories are spontaneously reactivated during sleep, leading to their gradual strengthening. Whether reactivation also mediates the integration of new memories with existing knowledge is unknown. We used targeted memory reactivation (TMR) during slowwave sleep (SWS) to selectively cue reactivation of newly learned spoken words. While integration of new words into their phonological neigh...
متن کاملA Theory on the Singular Function of the Hippocampus: Facilitating the Binding of New Circuits of Cortical Columns
Despite the hippocampus being extensively studied, controversy remains as to its role in cognitive processing. The current paper presents a theoretical argument that the hippocampus has only one purpose: the binding of parallel cortical circuits. The paper begins with a discussion of cortical columns as the common binary digit (bit) for all neocortical processing. This is followed by details on...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Neuron
دوره 62 شماره
صفحات -
تاریخ انتشار 2009